A review of methodology for sample size calculations in cluster randomised trials
نویسندگان
چکیده
Methods A systematic review is being conducted of sample size methodology for cluster randomised trials. The sources for the search include electronic databases PubMed and Web of Science, key text books on cluster randomised trials and discussions with experts in the field. The search strategy involves a compliment of Medical Subject Headings and free text terms to aid a comprehensive search. The references of papers eligible for the review will also be searched and a search on the first author conducted. This process will continue until no more additional papers are located. This work forms the beginning of a PhD research project.
منابع مشابه
A systematic review of cluster randomised trials in residential facilities for older people suggests how to improve quality.
BACKGROUND Previous reviews of cluster randomised trials have been critical of the quality of the trials reviewed, but none has explored determinants of the quality of these trials in a specific field over an extended period of time. Recent work suggests that correct conduct and reporting of these trials may require more than published guidelines. In this review, our aim was to assess the quali...
متن کاملSystematic review finds major deficiencies in sample size methodology and reporting for stepped-wedge cluster randomised trials.
BACKGROUND Stepped-wedge cluster randomised trials (SW-CRT) are increasingly being used in health policy and services research, but unless they are conducted and reported to the highest methodological standards, they are unlikely to be useful to decision-makers. Sample size calculations for these designs require allowance for clustering, time effects and repeated measures. METHODS We carried ...
متن کاملInternal and external validity of cluster randomised trials: systematic review of recent trials.
OBJECTIVES To assess aspects of the internal validity of recently published cluster randomised trials and explore the reporting of information useful in assessing the external validity of these trials. DESIGN Review of 34 cluster randomised trials in primary care published in 2004 and 2005 in seven journals (British Medical Journal, British Journal of General Practice, Family Practice, Preven...
متن کاملImportant considerations in calculating and reporting of sample size in randomized controlled trials
Background: The calculation of the sample size is one of the most important steps in designing a randomized controlled trial. The purpose of this study is drawing the attention of researchers to the importance of calculating and reporting the sample size in randomized controlled trials. Methods: We reviewed related literature and guidelines and discussed some important issues in s...
متن کاملInadequate reporting of sample size calculations in cluster randomised trials: a review
Results Of 166 trials, only 56 (34%) reported all key elements of sample size calculations in line with CONSORT recommendations. Elements specific to CRTs were the worst reported: the number of clusters or average cluster size was specified in only 94 (57%) and a measure of intracluster correlation coefficient (ICC) in only 86 (52%). Only 20 papers (12%) reported a priori and observed ICC value...
متن کامل